This book is a compilation of the policy briefs produced by the International Science Council's program on Urban Health and Wellbeing: A Systems Approach over the past five years. Intended for urban decision-makers at all levels, it highlights policy-relevant findings and research insights to encourage the co-creation of knowledge for healthy urban environments and people. The book shows how variations on the systems approach developed and promoted by the program have been implemented in regions around the world and contributed to improving urban health. These policy briefs summarize research findings and scientific events concerning urban health-related topics that are relevant for public health professionals, urban planners, urban stakeholder groups and the public at large.