This volume presents a collection of research studies on sophisticated and functional computational instruments able to recognize, process, and store relevant situated interactional signals, as well as, interact with people, displaying reactions (under conditions of limited time) that show abilities of appropriately sensing and understanding environmental changes, producing suitable, autonomous, and adaptable responses to various social situations. These social robotic autonomous systems will improve the quality of life of their end-users while assisting them on several needs, ranging from educational settings, health care assistance, communicative disorders, and any disorder impairing either their physical, cognitive, or social functional activities. The multidisciplinary themes presented in the volume will be interesting for experts and students coming from different research fields and with different knowledge and backgrounds. The research reported is particularly relevant for academic centers, and Research & Development Institutions.