Talking with God contains four of St. Alphonsus Liguori's works detailing the mysteries of the interior life: The Way to Converse with God, A Short Treatise on Prayer, Mental Prayer, and The Presence of God.

Within these works, St. Alphonsus stresses the importance of the inner life; the ease with which we can converse with God; on how the eternal truths are revealed to us; the absolute necessity of prayer, and how all is eventually lost without prayer. He directs us as to how to talk with God; explains how God answers us; how God listens to the prayers of everyone, and shows us how to continually have God's Presence with us throughout our day.

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