The trademark of this book is its highly readable introduction to the subject, its emphasis on core knowledge and its excellent four-color artwork. On the tenth edition, Ivan Roitt is joined by Peter Delves, a brilliant teacher from University College London. Together they have extensively updated all aspects of the book to produce a new edition, which will be an invaluable resource to students of immunology and medicine.

The tenth edition focuses on:

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• dendritic cells
  
• intraepithelial lymphocytes
  
• NKT and gd T-cells
  
• NK receptors
  
• non-classical MHC presentation of non-peptidic antigens
  
• analysis of TCR-peptide-MHC interactions
  
• gene 'knockouts' and 'knockins'
  
• cell signaling pathways
  
• chemokines and their receptors
  
• intimate links between innate and adaptive immunity
  
• regulatory T-cells
  
• Fcg receptors
  
• activation-induced cell death
  
• signaling through pattern recognition systems
  
• prions
  
• DNA vaccines
  
• mucosal adjuvants
  
• molecular understanding of immunodeficiency
  
• CCR5 co-receptor for HIV
  
• therapeutic benefit of monoclonal anti-IgE in allergy
  
• the excessive hygiene hypothesis
  
• induction of antigen-specific tolerance for transplantation
  
• heat-shock proteins in tumor immunity and autoimmunity
  
• peptide priming of dendritic cells for immunotherapy
  
• thymic expression of organ-specific autoantigens

Roitt's Essential Immunology is supported by a web site at www.roitt.com This useful on-line resource contains self-assessment material, future updates, further reading and an image archive.

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• New edition of a best-selling textbook - known internationally by both students & faculty.
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• Completely updated throughout.
  
• Greater emphasis on core knowledge & ease of use.
  
• Supported by a free on-line www.roitt.com companion containing updates, images and self-assessment material.