Neural Control of Renal Function
Format: Paperback
ISBN13: 9781615047758
Paperback|9781615047758
✨ Featured Offer
Brand New
$53.76
List Price: $49.95
🚚
See all 5 offers from $32.13 FREE standard delivery by: 01 Apr 2026
Overview
The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Under normal conditions, the renal mechanosensory nerves activated by stretch of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.
| ISBN-13 | 9781615047758 |
|---|---|
| ISBN-10 | 1615047751 |
| Weight | 1.16 Pounds |
| Dimensions | 7.50 x 0.25 x 9.25 In |
| List Price | $49.95 |
| Edition | 2nd Edition |
| Format | Paperback |
|---|---|
| Language | English |
| Pages | 106 pages |
| Publisher | Morgan & Claypool |
| Published On | 2018-07-30 |
View All Offers
Sort by:
Price
Condition
Seller
Seller Comments
Price
Used, Very Good
Seller details
Suffolk Books
center moriches, ny, USA
Fast Shipping-Safe and Secure 7 days a week!
Free delivery by: 01 Apr 2026
✨ Brand New
Seller details
Alibris
Sparks, NV, USA
Print on demand Trade paperback (US). Glued binding. 106 p. Colloquium Integrated Systems Physiolog...
Free delivery by: 01 Apr 2026
Used, Good
Seller details
Bonita
Santa Clarita, CA, USA
Access codes and supplements are not guaranteed with used items. May be an ex-library book.
Free delivery by: 01 Apr 2026
Brand New
Seller details
GreatBookPrices-
Columbia, MD, USA
100% Money Back Guarantee. Brand New, Perfect Condition. We offer expedited shipping to all US locat...
Free delivery by: 01 Apr 2026
Used, Like New
Seller details
GreatBookPrices-
Columbia, MD, USA
100% Money Back Guarantee. Brand New, Perfect Condition. We offer expedited shipping to all US locat...
Free delivery by: 01 Apr 2026