In the spring of 1974, Calliope Stephanides, a student at a girls' school, Grosse Pointe, MI, finds herself drawn to a chain-smoking, strawberry-blonde classmate with a gift for acting. The passion that furtively develops between them - along with Callie's failure to develop - leads Callie to suspect that she is not like other girls. The explanation for this shocking state of affairs takes us out of suburbia - back before the Detroit race riots of 1967, before the rise of the Motor City, to1922, when the Turks sacked Smyrna and Callie's grandparents fled for their lives, back to a tiny village in Asia Minor where two lovers, and one rare genetic mutation, set in motion the metamorphosis that will turn Callie into a being both mythical and perfectly real: a hermaphrodite.

Sprawling across eight decades - and one unusually awkward adolescence - Jeffrey Eugenide's long-awaited second novel is a grand, utterly original fable of crossed bloodlines, the intricacies of gender, and the deep, untidy promptings of desire.