This book presents eleven peer-reviewed papers from the 3rd International Conference on Applications of Mathematics and Informatics in Natural Sciences and Engineering (AMINSE2017) held in Tbilisi, Georgia in December 2017. Written by researchers from the region (Georgia, Russia, Turkey) and from Western countries (France, Germany, Italy, Luxemburg, Spain, USA), it discusses key aspects of mathematics and informatics, and their applications in natural sciences and engineering. Featuring theoretical, practical and numerical contributions, the book appeals to scientists from various disciplines interested in applications of mathematics and informatics in natural sciences and engineering.