This book includes selected papers from the International Conference on Machine Learning and Information Processing (ICMLIP 2019), held at ISB&M School of Technology, Pune, Maharashtra, India, from December 27 to 28, 2019. It presents the latest developments and technical solutions in the areas of advanced computing and data sciences, covering machine learning, artificial intelligence, human-computer interaction, IoT, deep learning, image processing and pattern recognition, and signal and speech processing.