After meeting at a truck driving school, two novice truck drivers, Lance Getty and former detective sergeant Wil Fox, start team driving and run up against the cargo hijacking industry. The hijackings are part of an Al Qaeda plan to bring murder and mayhem to the United States by blowing up four hydroelectric dams on the West Coast.

With backup from the FBI, the truckers clash with the hijackers and Al Qaeda in the Nevada desert, lighting up the night sky with a stunning pyrotechnic display. But who will make it out alive? And will the United States ever be safe again?