Based on the proceedings of the 2nd International Conference on Intelligent Human Systems Integration (IHSI 2019), held on February 7-10, 2019, in San Diego, California, USA, the book also examines the forces that are currently shaping the nature of computing and cognitive systems, such as the need to reduce hardware costs; the importance of infusing intelligence and automation; the trend toward hardware miniaturization and power reduction; the need for a better assimilation of computation in the environment; and social concerns regarding access to computers and systems for people with special needs. It offers a timely survey and a practice-oriented reference guide for policy- and decision-makers, human factors engineers, systems developers and users alike.