On the eve of his hotly contested reelection campaign in Cascade County, Oregon, Sheriff Jason Pruett finds himself in the midst of an unprecedented crime wave. The richest man in town has been murdered, his neck broken my someone--or something--with extremely large, powerful hands. Sheriff Pruett races against time to find the killer(s), while the victim's company--Paul Bunyan Logging--faces violent opposition from radical environmentalists and a Native American tribe bent on preserving their homeland's virgin forest at all costs. A tribal shaman claims that he has conjured Omah, a vengeful nature spirit better known to Cascade County's white inhabitants as Sasquatch or Bigfoot. Sheriff Pruett is a skeptic, but as mayhem escalates around him, claiming other lives, he must follow every lead available to solve the crime and restore order.

Hopsquatch is a modern mystery set against the background of Amerindian legend, cryptozoology (the search for "hidden" animals), and clashes mirroring real-life headlines from the rural battlegrounds where tradition stands against the march of "progress," often with explosive results.