This first full biography confirms Florine Stettheimer as one of the 20th century's most significant, progressive artists whose work remains highly relevant today. Stettheimer was a feminist, multi-media artist who painted several sexually explicit, political, identity-issue-based works and documented New York City's growth as the centre of cultural life, finance, and entertainment between the World Wars.

During her first 40 years in Europe, Florine Stettheimer studied academic painting and was aware of all the earliest modernist styles prior to most American artists. Returning to New York, she and her sisters led an acclaimed Salon for major avant-garde cultural figures including Duchamp, the Stieglitz circle, poets, dancers, writers, etc. During her life she showed her innovative paintings in over 46 of the most important museum exhibits and Salons, wrote poetry, designed unique furniture and gained international fame for her sets and costumes for the avant-garde opera, 4 Saints in 3 Acts.