This book constitutes the refereed proceedings of the 10th International Symposium on Engineering Secure Software and Systems, ESSoS 2018, held in Paris, France, in June 2018. The 10 papers, consisting of 7 regular and 3 idea papers, were carefully reviewed and selected from 26 submissions. They focus on the construction of secure software, which is becoming an increasingly challenging task due to the complexity of modern applications, the growing sophistication of security requirements, the multitude of available software technologies, and the progress of attack vectors.