James Bond travels to the Caribbean to investigate the mysterious disappearance of a secret service team. As he uncovers the astonishing truth about strange energy waves that are interfering with U.S. missile launches, he must battle deadly assassins, sexy femmes fatales, and even a poisonous tarantula. The search takes him to an exotic tropical island, where he meets a beautiful nature girl and discovers the hideout of Doctor No, a six-foot-six madman with a mania for torture, a lust to kill, and a fantastic secret to hide.