Martin Arrowsmith, brilliant but licentious, makes his way from his small Midwest town to New York City. Getting his start at medical school, Martin sets out on a series of affairs, bouncing from woman to woman and job to job, hungry to satisfy his desires as both a man and a man of science. Just as it appears he'll be able to settle down, he finds himself back among the scientific elite and faced with a discovery that can change his life.

Written in conjunction with science writer Paul de Kruif, Arrowsmith is one of the first books to address the culture of science in a period of medical education reform. A critical and commercial success, the book earned Sinclair Lewis the 1926 Pulitzer Prize, which the author would go on to decline.

Professionally typeset with a beautifully designed cover, this edition of Arrowsmith is a classic of science literary fiction, reimagined for modern readers.