Overview

Apoptosis is a regulated form of cell demise that can be induced or blocked by groups of specific stimuli. Occurring in all living tissues, it is thought critical to the maintenance of homeostasis and is implicated in lowering susceptibility to tumour growth. Conversely, over-sensitivity to apoptotic triggers can cause cells to be lost inappropriately from tissues, as appears to occur in neurodegenerative diseases.This book examines the molecular pathways regulating apoptosis, progressing from the nematode worm through Drosphila to the more complex pathways evident in mammalian cells. Differences in the cell death pathway within specific tissues are addressed, as are the different genes that may act to regulate progressive steps.

ISBN-13

9780199638505

ISBN-10

0199638500

Weight

2.05 Pounds

Dimensions

9.80 x 0.90 x 7.40 In

List Price

$225.00

Edition

1st Edition

Format

Hardcover

Language

English

Pages

346 pages

Publisher

Oxford University Press

Published On

2002-06-20



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