Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity
Format: Paperback
ISBN13: 9780120890309
Paperback|9780120890309
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Overview
Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations.
| ISBN-13 | 9780120890309 |
|---|---|
| ISBN-10 | 0120890305 |
| Weight | 1.23 Pounds |
| Dimensions | 5.88 x 1.00 x 9.00 In |
| List Price | $107.00 |
| Edition | 1st Edition |
| Format | Paperback |
|---|---|
| Language | English |
| Pages | 384 pages |
| Publisher | Academic Press |
| Published On | 1999-10-22 |
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