This book discusses the latest advances in digital modeling systems (DMSs) and additive manufacturing (AM) technologies. It covers applications of networked technologies, ubiquitous computing, new materials and hybrid production systems, discussing how they are changing the processes of conception, modeling and production of products and systems of product. The book emphasizes ergonomic and sustainability issues, as well as timely topics such as DMSs and AM in Industry 4.0, DMSs and AM in developing countries, DMSs and AM in extreme environments, thus highlighting future trends and promising scenarios for further developing those technologies. Based on the AHFE 2019 International Conference on Additive Manufacturing, Modeling Systems and 3D Prototyping, held on July 24-28, 2019, in Washington D.C., USA, the book is intended as source of inspiration for researchers, engineers and stakeholders, and to foster interdisciplinary and international collaborations between them.