This edition provides a reference work for running an effective, state-of-the-art diagnostic laboratory. Guiding the clinical microbiologist in the selection, performance, and interpretation of laboratory procedures, the book focuses on the when and why of diagnostic procedures, as well as the how. It presents a direct approach to organizing information with thorough but concise treatments of all the major areas of microbiology, including microbial discoveries, changing diagnostic methods, and emerging therapeutic challenges facing clinicians.