The scope and coverage of psychophysiology has expanded tremendously over recent years and this revised and expanded Handbook of Psychophysiology provides both a context for and coverage of the biological bases of cognition, emotion, and behavior at a level of scholarship informative to the specialist and accessible to the student. The book is divided into six sections covering topics such as the history of psychophysiology, systemic psychophysiology ranging from the peripheral nervous system to the neuroendocrine and immune systems, principles of human behavior that have emerged from psychophysiological analyses, applications, and methodology. The final section provides detailed coverage of emerging topics in psychophysiology, including functional magnetic resonance imaging. This revised and expanded edition of the Handbook of Psychophysiology replaces Principles of Psychophysiology as an essential reference for students, researchers, and professionals in psychophysiology, psychology, psychiatry, neuroscience, and related biological and behavioral sciences.