Retinoic Acid Structure, Mechanisms, and Roles in Disease

ISBN-10: 1621005976
ISBN-13: 9781621005971
Authors: Li-Hong Cheng, Yuto Ito
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Retinoic acid (RA) is a signaling molecule involved in many important pathways in every cell. When RA binds to RA receptors and activates them, cell cycle arrest, differentiation and apoptosis can occur. In this book, the authors present topical research in the study of the structure, mechanisms and roles in disease of retinoic acid. Topics discussed include retinoid signaling in mammalian inner ear development; nuclear receptors for retinoids involved in the control of expression activity of p-glycoprotein; retinoic acid signaling and immunotherapy of cancer; using retinoic acid in molecular medicine and retinol/vitamin A signaling and self-renewal of stem cells.

Author bio:

Steven Vogel is a James B. Duke Professor Emeritus of biology at Duke University. His most recent books include Cats' Paws and Catapults and Glimpses of Creatures in Their Physical Worlds.


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Product details

Binding: Hardcover Publisher: Nova Science Publishers, Incorporated Number of pages: 202 Dimensions: 7.00" wide x 10.00" long x 0.50" tall Weight: 1.320 lbs. Language: English